PhD-project
- Sadaf aims to conduct research which is neuroscientifically sound, technologically fueled and clinically relevant.
Functional Ultrasound (fUS)-imaging
Neurosurgery relies heavily on making continuous, intra-operative tumor-brain delineations. Currently available imaging and mapping techniques such as (f)MRI, DTI and ESM present with serious limitations including lack of real-time intra-operative feedback, lack of depth resolution and risks of epileptic seizure elicitation. Functional ultrasound (fUS) presents as a new mobile neuro-imaging tool with unprecedented spatiotemporal resolution, which allows for possible identification of tumor borders based on vascular strucuture, as well as a distinction between healthy functional and unhealthy tumor tissue, based on differences in vascular response during particular functional tasks performed by the patient.
Neuromodulation in Spinal Cord Injury (SCI)
Current strategies for motor recovery after spinal cord injury (SCI) aim to facilitate motor performance through modulation of afferent input to the spinal cord using epidural electrical stimulation (EES). The dorsal root ganglion (DRG) itself, the first relay station of these afferent inputs, has not yet been targeted for this purpose. In this project we study whether DRG-stimulation can facilitate clinically relevant responses in motor complete SCI.